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NFL Week 10 odds and predictions: Dolphins vs. Colts, Commanders vs. Giants, full schedule

By November 12, 2026
DETROIT, MICHIGAN – AUGUST 22: A detail of the NFL logo on The Duke Wilson football ball before a preseason game between the Washington Commanders and Detroit Lions at Ford Field on August 22, 2026 in Detroit, Michigan. (Photo by Nic Antaya/Getty Images) | Getty Images

The Miami Dolphins and Indianapolis Colts face off in Week 10 in a game that could decide the first overall pick in the 2027 NFL Draft. The Colts arrive in Miami as sellers at this week’s trade deadline, looking to bolster their draft assets and build for the future rather than continuing to try to win now. The Dolphins, having held steady at the deadline, looked positioned to take advantage of the Colts’ semi-fire-sale, only to suffer major losses due to injury: quarterback Malik Willis and defensive tackle Zach Sieler both landed on injured reserve this week.

The Dolphins remain underdogs for Sunday’s game, with the line growing from 2.5 points up to 3.5 after the injuries. Will they pull off the upset on the road to improve to 2-7? Or will the Colts come away with their third win this year?

Each week, our contributors make their straight-up winners predictions for every game on the schedule. You can check out our picks below, as well as join in the pool as a member of The Phinsider community through the widgets provided by Tallysight.

All odds from FanDuel Sportsbook as of publication. Lines may move throughout the week.

Miami Dolphins at Indianapolis Colts (-3.5)
Sunday, 1 p.m. ET

Week 10 – 2026 schedule

Bye Week

Chicago Bears
Denver Broncos
Philadelphia Eagles
Tampa Bay Buccaneers

Thursday Night Football (8:15 p.m. Eastern)

Washington Commanders at New York Giants

Sunday picks

9:30 a.m. Eastern

New England Patriots vs. Detroit Lions (-2.5) – Munich, Germany

1 p.m. Eastern

Buffalo Bills (-7.5) at New York Jets
Carolina Panthers at New Orleans Saints (-2.5)
Minnesota Vikings at Green Bay Packers (-3)
Kansas City Chiefs (-3.5) at Atlanta Falcons
Houston Texans (-4.5) at Cleveland Browns
Jacksonville Jaguars (-10.5) at Tennessee Titans

4:05 p.m. Eastern

Los Angeles Rams (-9.5) at Arizona Cardinals
Seattle Seahawks (-6.5) at Las Vegas Raiders

4:25 p.m. Eastern

San Francisco 49ers (-4.5) at Dallas Cowboys

Sunday Night Football (8:20 p.m. Eastern)

Pittsburgh Steelers at Cincinnati Bengals (-3.5)

Monday Night Football (8:15 p.m. Eastern)

Los Angeles Chargers at Baltimore Ravens (-4.5)

All odds via FanDuel Sportsbook


Week 7 Results

Sumeet Jena (15-0)
Marek Brave (14-1)
James McKinney (14-1)
Kevin Nogle (14-1)
The Phinsider Community (14-1)


2026 Overall Standings

(Through Week 9)

James McKinney (93-42-1)
Marek Brave (90-45-1)
The Phinsider Community (85-50-1)
Kevin Nogle (84-51-1)
Sumeet Jena (76-59-1)*

*Sumeet Jena’s overall record reflects the nine games he did not pick in Week 2 as losses.

https://sports.yahoo.com/articles/nfl-week-10-odds-predictions-235448211.html

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